The 62 year-old opens up about living with Bipolar I (with psychotic episodes and rapid cycling), battling alcoholism, being in abusive relationships, being married 5 times, having a son with Schizo-Affective Disorder and getting support from her sister, actress Glenn Close. Jessie and Glenn co-wrote the book Resilience: Two Sisters and a Story of Mental Illness. and started the foundation to advocate for people with mental illnesses Bring Change 2 Mind.