A small dog is abandoned by his owner, joins a pack of strays, is picked up by animal control. He is adopted by a kindly retired couple and bonds with them. He is thrown from a car in a highway accident and wanders off in a daze. He ends up going on a four thousand mile trek filled with adventure and danger. On his journey he makes many human and animal friends, but also meets many dangerous enemies--also both human and animal. All the while he is trying to return home to the couple he loves.
If you liked Lassie or Lady and the Tramp, you'll like Whiskers.