Who is Andrea Bern? When her therapist asks the question, Andrea knows the right things to say: she’s a designer, a friend, a daughter, a sister. But it’s what she leaves unsaid—she’s alone, a drinker, a former artist, a shrieker in bed, captain of the sinking ship that is her flesh—that feels the most true. Everyone around her seems to have an entirely different idea of what it means to be an adult: her best friend, Indigo, is getting married; her brother—who miraculously seems unscathed by their shared tumultuous childhood—and sister-in-law are having a hoped-for baby; and her friend Matthew continues to wholly devote himself to making dark paintings at the cost of being flat broke. But when Andrea’s niece finally arrives, born with a heartbreaking ailment, the Bern family is forced to reexamine what really matters. Will this drive them together or tear them apart?